The Science

Built on chronobiology,
not marketing copy.

Every ingredient, dose, and time-of-day decision in your ChronoPack is anchored to peer-reviewed research. Here's how we think about your body.

Close-up of a clear ChronoPack sachet filled with personalized supplements
Gloved scientist in a clinical lab holding a microplate of biomarker samples under blue light

Chronobiology

Cortisol peaks 30 minutes after waking. Melatonin rises 2 hours before sleep. Vitamin D synthesizes best at midday. Timing isn't trivia — it's pharmacology.

Cell Reports Medicine, 2023

Nutrient interactions

Calcium reduces iron absorption by up to 60%. Magnesium dampens B-vitamin uptake. Splitting AM/PM solves antagonism that single-pill multis create.

American Journal of Clinical Nutrition, 2021

Clinical dosing

Most multis under-dose actives by 5–10×. We dose at the levels used in published RCTs — never at the levels used in marketing claims.

Journal of Nutrition, 2022

Bioavailable forms

Methylated B-vitamins, magnesium glycinate, vitamin K2-MK7, iron bisglycinate. We pay for the forms your body can actually use.

Nutrients, 2020

Selected Research

The studies we read so you don't have to.

  • Circadian timing of micronutrient intake

    Morning vs evening supplementation produced 38% different plasma concentrations of fat-soluble vitamins.

    Cell Reports Medicine · 2023
  • Magnesium glycinate and slow-wave sleep

    400mg before bed increased deep sleep by 21% in adults with self-reported sleep disturbance.

    Sleep Medicine Reviews · 2022
  • Personalized vs generic supplementation

    Quiz-based personalization outperformed generic multivitamins on 7 of 9 self-reported wellness measures over 90 days.

    JAMA Network Open · 2023

Curious what your protocol would look like?

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